In 2015, HKUST launched its Robotics Institute, a major new multidisciplinary research initiative. The Institute supports the endeavors of faculty and students working on robotics and autonomous systems across the campus. Building on years of research, a network of alumni, and a vibrant regional economy, the Robotics Institute draws on innovations in sensors, devices, systems, networks, neuro-sciences, data analytics, and machine learning to catalyze new research by faculty and students in smart manufacturing, transportation, safety, healthcare, and a range of other applications that can benefit society.

In June 2021, the Institute was renamed the Cheng Kar-Shun Robotics Institute, following a generous donation from Chow Tai Fook Charity Foundation Limited to HKUST to support academic and research development.