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Mutant frequency trajectories exhibit complex dynamics due to linkage affects. Top left panel shows frequency trajectories of all mutant alleles, the lower three panels on the left show the trajectories of beneficial/neutral/deleterious mutants in blue/orange/red. The right panel shows their estimated fitness values using the proposed inference method. Vertical lines indicate the true fitness values.
Better Treatments Against HIV
New Method Identifies Adaptive Mutations in Complex Evolving Populations
01/12/2020
(From left) Prof Bertram Shi, Head of HKUST’s Department of Electronic & Computer Engineering (ECE); Prof Matthew McKay, Hari Harilela Associate Professor in the Departments of ECE and Chemical & Biological Engineering; and Prof Raymond Louie, Research Assistant Professor in the Department of ECE and Junior Fellow of HKUST Institute for Advanced Study
Decoding of Crucial HIV Protein Raises Hope of Modifying Vaccine
HKUST Researchers Discover Fitness Landscape of HIV Envelope Protein That May Help Vaccine Development
07/02/2018
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